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Transfer Factor™ by 4Life™ Research is extracted from the colostrum of our own herd of Grade A dairy cows. 4Life™ has licensed the patent which identifies transfer factor in colostrum and the exclusive and proprietary method for extracting transfer factor from colostrum (US Patent 4,816,563). Each batch of 4Life™ Transfer Factor™ is tested to ensure transfer factor quality and activity.
 

General Questions:

Who should take Transfer Factor™:

How much and how often to take Transfer Factor™:

Scientific Research:

Product Purity:

The Source of our Transfer Factor™:

Product Storage:

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If an individual should choose to use Transfer Factor™, their immune system may be supported in ways that it otherwise would not. Transfer factors work as instructors to the different members of the immune system. This instruction assists the function of the immune system in recognizing and fighting outside threats to your health. Transfer factors are immune modulators, which means that they are able to support healthy immune function by an Inducer Factor as well as a Suppressor Factor. In addition, an independent study showed that 4Life™'s Transfer Factor™ was shown to increase the Natural Killer cell (NK)activity by more than 100%. This is an important discovery in that NK cells carry the immune messaging cytokines, which direct battle with outside threats. When NK cell count is increased the immune system is working more effectively.

Transfer Factor Plus™ is different from Transfer Factor™ in that it has additional ingredients. These ingredients include cordyceps, IP-6, maitake mushrooms, beta glucan, zinc, and shiitake mushrooms that help initiate a stronger stimulating immune response than that of Transfer Factor™. Transfer Factor Plus™ strengthens both the innate immune system (the immune information an individual is born with) and the adaptive immune system (the immune information an individual's immune system has obtained throughout life). For your individual condition, either or both of these products may be of benefit to you because of its supporting and strengthening. If you choose to use these products, please consult your physician to make sure there will be no complications or interactions associated with your current state of health.

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There have been no adverse responses reported while taking Transfer Factor during pregnancy. As with all supplements, consult a physician before use.

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Yes, in preparing Transfer Factor™ the large molecular proteins are removed, including casein and antibodies. Milk allergies are caused by the large proteins in milk, primarily casein and to a lesser extent antibodies.

Gluten is another extracted protein and is predominately isolated from wheat, rye and barley. Because Transfer Factor XF is extracted from colostrum, gluten is not found in Transfer Factor™.

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Transfer Factor Plus™ contains a component derived from baker's yeast called beta glucans. Transfer Factor Plus™ does not contain whole yeast however.

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Yes, TF Kids™ contains 150 mg of Transfer Factor XF™ per tablet where Transfer Factor™ capsules contain 200mg each capsule. Because of the weight differential between adults and children, TF Kids™ contains less Transfer Factor XF™. Instructions concerning serving size may be found on the TF Kids™ labels.

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Ideally Transfer Factor™ should be used daily to continually work to support the immune system. If you discontinue taking Transfer Factor™ your immune system will miss out on its daily support.

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There is no known toxicity level associated with Transfer Factor™.

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Generally, the effects are very similar no matter how transfer factors enter the body. Because transfer factors originate in the blood, the source of transfer factors is identical whether they reenter the body in concentrated form such as 4Life™ Transfer Factor™, or by injection.

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In vitro, means "out of the body". This means that substances are tested on extracted cells that have been removed from the body. In vivo means that substances are placed into the body and the results are measured "in the body."

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This process is how Dr. Lawrence discovered transfer factors. He took the white blood cells (leukocytes) from a previously infected tuberculosis patient, who has regained their health, and injected these white blood cells into a recently infected patient. The white blood cells from the "old" TB patient contain information on how the immune system fights against the disease and transferred this information to the "new" patient.

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4Life has made available three booklets containing condensed information from the volumes and volumes of research available on Transfer Factor™ and the components that were brought together in Transfer Factor Plus™. The first booklet is ""Transfer Factor" by William Hennen, Ph.D. the second is called ""Enhanced Transfer Factor", also by Dr. Hennen. A third booklet by a member of 4Life's Medical Advisory Board, Rita Elkins, MH, is also entitled "Transfer Factor", and is written in layman's terms so the general population can gain additional knowledge. Each of these booklets contains hundreds of additional references.

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4Life™ extracts Transfer Factor™ from cow colostrum because it is an immense and available source. Transfer factors are non-species specific, meaning they can be used in humans even if the original source is a different mammal.

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Yes, Transfer Factor™ can be given to animals, including horses. TF Pets™ is available for canines and felines, but regular Transfer Factor™ can be taken by any animal. Remember when you are calculating serving size for animals that they have a much more "heroic" and responsive immune system. Animals, especially the grazers, are much more immunologically responsive and can get by with less Transfer Factor™ per pound. The immune system has a way of amplifying the signal. Serving sizes for larger animals do not always correspond to weight entirely, especially when you are dealing with grazers. Start your animal on a minimal amount and continue to increase the serving over time, if necessary.

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The transfer factors we received as infants are just purposeful as those available in Transfer Factor™. As infants, mother's colostrum gave immune information while our immune systems were not fully developed, but the transfer factors were absorbed into the bloodstream and eventually were used up to become part of the functioning immune system, consisting of lymphocytes, natural killer cells, macrophages, etc. The information provided at birth was to work against the specific threats experienced by your mother at that time; after years of life new threats to the immune system exist. By using oral transfer factor we are providing the same type of immune information we received at birth.

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Unfortunately, 4Life™ is unable to prescribe specific supplements for identified conditions; we are only able to describe system function that may be supported through supplementation. Overall, Transfer Factor and Transfer Factor Plus are designed to support normal immune function. Additional information is available in "Transfer Factor" or "Enhanced Transfer Factor" by William Hennen, Ph.D.

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Yes, TF Renewall has been formulated for external application to support the body's first line of immune defense: the skin. Please consult with a physician for information on specific skin conditions.

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Transfer Factor has been consumed for many years with no reported side effects. Studies have shown no toxicity. The recommended maintenance amount is 3 capsules a day.

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Some individuals do use more for added immune support during short duration. The best and safest way to begin using Transfer Factor Plus™ is to use the recommended serving size as listed on the product label.

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Long-term exposure to high temperatures can degrade potency and possibly neutralize Transfer Factor™ activity. Transfer Factor should be stored in a cool, dry environment.

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Yes. The large proteins, such as lactose, are filtered out during the extraction process. Are transfer factors made of sugars, proteins or fats? Isolated transfer factors have been determined to be a chain of small peptides consisting of 44 amino acids. Amino acids are the building blocks of proteins.

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The immune system is challenged during times of stress. Because of this, additional support through supplementation may promote a healthy immune system. When the immune system is working effectively, recovery occurs at an ideal pace. The use of Transfer Factor™ or Transfer Factor Plus™ is appropriate at anytime you feel your immune system has been compromised.

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Transfer factor is good for everyone who needs an extra immune boost. The three groups who are most in need of immune strengthening are the young, the old, and anyone under stress. Almost all of us fall into one of these categories. We often talk of the baby-boom generation. Most of these people are at an age where already their immune systems are becoming lax. Transfer factor is a way to boost a lagging immune system.

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I think that is exactly what we are seeing in many countries, notably China, Czechoslavakia, Germany, Hungary, Poland, and Japan. In the US, transfer factor has had an interesting history. The idea of transfer factor flies in the face of conventional immunology. In the 1950's, antibiotics were the golden child of medicine, followed in the 60's by steroids like cortisone for inflammation and the synthetic steroid hormones like ethinyl estrogen and progestin that were used to create the birth control pill. After an initial delay, transfer factor hit its heyday in the 70's and early 80's. Results, however, were inconsistent as researchers dove in sometimes with more enthusiasm than skill. The key feature that was missing in these investigations was a dependable assay technique for quality control of the product. The quality control issue was not resolved until the mid 1980's. Given that transfer factor is not a single entity, the pharmaceutical companies had fits trying to purify the material without losing efficacy. This attempted force-fit into the single-entity, single-function drug dogma was disastrous. The next issue that slowed transfer factor research is the age-old issue of funding. When AIDS hit the popular press, politicians shifted funding into AIDs research, but with focus on finding the cause and then finding a drug that would cure AIDs. The work of a few, dedicated, but under-funded researchers and the inability of the mainstream medical-pharmaceutical industry have combined to again focus attention on transfer factor as one of the few modalities that is effective against diseases of viral origin.

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Yes, there are two doors that recently have opened that allow transfer factor to be effectively marketed now. The first door to open was the passage of the DSHEA (Dietary Supplement Health and Education Act) in 1994. The provision for structure-functions claims allows the story of transfer factor to be told without jeopardizing its status as a nutritional supplement. The second is technical. Transfer factor was definitely an idea way ahead of its time and it had to wait for technology to catch up. The processing methods that allow for large scale extraction of transfer factor have only recently been perfected, and a commercial product has only been available for the last three years.

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Foods and dietary supplements are not approved per se by the FDA. Food supplements derived from milk would certainly fall under the category of Generally Recognized As Safe (GRAS).

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YES. Researchers have given huge doses of transfer factor to volunteers in an attempt to trigger some sort of adverse reaction. No negative side effects were observed, even with massive doses.

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Colostral transfer factor was designed by nature for newborns. Removal of the milk allergens and lactose leaves the essence of the immunologic information in the form of transfer factor.

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Raw Product Quality - Transfer Factor™
By Richard H Bennett, Ph.D.
Expert in Infectious Disease Microbiology


As the interest in 4Life™ Research Transfer Factor™ products increases globally, questions arise from time to time about the quality of the raw ingredients, especially the colostrum from which Transfer Factor™ is extracted.

In response to the questions, the following points are considered:

  1. All of the dairy herds that produce colostrum for processing are US FDA and USDA Grand A dairy farms. As such the farm and milk must meet the standards of state and federal milk quality ordinances, including the Pasteurized Milk Ordinance (PMO). These state and federally inspected farms produce milk for the Grade A Fluid Milk Market. Milk from these farms is sold in the market.

  2. It is unlawful to use antibiotics in lactating dairy cattle that will give rise to violable levels of antimicrobial drugs. All tanker truckloads of milk are tested in all processing plants for violable residues. Contaminated milk cannot be used for fluid or processing milk purposes. The financial penalties are severe and dairy producers have redundant management schemes in place to assure that residues do not occur. USDA and FDA statutes prohibit use of antibiotics as a feed supplement in lactating dairy cattle.

  3. Our inquiry revealed that the dairy farms that produce raw colostrum for processing do not use hormones intended to increase milk production, including rBST.

  4. All colostrum is pasteurized in a proprietary process to assure its microbial safety and quality. Moreover, the ultra-filtration process will remove all known microorganisms. Once dried the powder is tested for viable microbes.

  5. The agent associated with "Mad Cow Disease" (Bovine Spongiform Encephalopathy, BSE) has NOT been identified in the United States dairy herd. Additionally, there is no evidence of milk borne transmission in the English experience with BSE and the 36 Crutzfeldt-Jakobs Disease (CJD) patients.

  6. All other ingredients in the Transfer Factor™ product line are "Food Grade" as defined by the US FDA Center for Food Safety and Applied Nutrition and meet the US FDA GRAS (Generally Regarded As Safe) definition.

  7. All products and processing meet the requirements of the Good Manufacturing Practices (GMPS) Ordinance.

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Relieving Concerns about the "Mad Cow Disease"
By Richard H. Bennett, Ph.D.
Expert in Infectious Disease Microbiology


Over the last year, medical professionals and customers alike have raised questions about the safety of Transfer Factor™ products. Many of the questions are about TSE's (Transmissable Spongio encephalopathies). This concern arises from the events that have taken place in England over the last 14 years.

In 1986 over 160,000 cases of bovine neurological disease were confirmed in sick cattle in Europe. The disease is called Bovine Spongiform Encephalopathy or BSE. The common linkage of this disease outbreak was the practice of feeding rendered animal waste products back to beef cattle. The infective agent is likely a Prion or a viral-like particle. The agents that cause TSE's have not been fully identified. Just the same the BSE agents withstand heat processing of normal cooking and pasteurization. Once ingested they have the ability to infect cells, especially neurological tissues, and reproduce themselves.

The BSE agent is highly species specific as it infects the bovine almost exclusively. The concern about BSE and human health arose from a statistical linkage that suggested that a variant of the BSE agent was able to cause the human equivalent of BSE called Creutzfeldt-Jakob Disease or CJD. CJD has a genetic predisposition component and occurs worldwide at a rate of 1 per million persons. CJD has been linked to the use of Human Growth Hormone (HGH) use and transplantation of neurological tissue.

In England a variant form of CJD was identified in 14 patients as of 1996. In contrast to typical CJD, this variant affected young patients. Rigorous scientific review concluded that no definite link between BSE and the CDJ variant could be established. Circumstantial evidence suggested that consumption of meat containing the BSE agent was the likely cause. Thousands of English and European consumers were likely exposed, yet only 14 human cases have been confirmed. Milk and dairy products did not appear to be a linkage to the disease and are considered safe by UK authorities.

Worldwide surveillance for BSE reveals there are a few other countries that have low incidence of BSE in cattle. THERE HAVE BEEN NO CASES OF BSE IN THE UNITED STATES EVER. Internal surveillance for BSE is intense due to the potential devastating impact of the disease on the milk and meat industries.

There are TSE's in other animals in the US, including cats, mink, deer, elk, sheep and goats. There is no evidence of horizontal transmission to humans from these species.

The US meat and milk supply is considered by the USDA and WHO to be free of the BSE agent. Most importantly protections are now law. BSE is a noticeable disease and veterinarians are required to report suspect cases. Hundreds of cattle brains in the US are examined each year for evidence of BSE. There have been no confirmed cases from this screening process.

In August of 1997 the FDA instituted regulations that prohibit the refeeding of most animal proteins to cattle and other ruminants. Feeding animal protein to milk cows has never been recommended and has not been the practice of the dairy producer.

In summary, we should have great confidence that all colostrum and bovine sources of thymus protein are not contaminated with the BSE agent. The programs and regulations currently in place will work effectively to ensure product safety for 4Life™ products derived from animal sources.
 

4Life™ Bovine Derived Materials and Bovine Spongioform Encephalophathy (BSE)
Dr. C.W. McCausland
Director of Research and Development


BSE has been a fairly publicized issue recently; however, the discovery of BSE dates back to 1981. To date, there has never been any incident of BSE in the United States. Because there is no practical method of detection for BSE, the best way to insure a safe product containing bovine derived materials is to avoid purchase of materials from countries that have reported BSE incidence.

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